Advertisement
Survey Series
Institutions
For Advertisers
|
|
||||
|
New T-cell epitope math
Email: David Secko - dmsecko@interchange.ubc.ca News from The Scientist 2004, 5(1):20040116-01
|
||||
|
|
||||
|
When predicting T-cell epitopes from a protein—a useful technique for cancer and vaccine research—it has been generally thought that theoretically chopping the proteins into eight- to ten-amino acid fragments would give all its possible epitopes. But in the January 15 Nature, Ken-ichi Hanada and colleagues from the National Institutes of Health have discovered that the posttranslational splicing of protein fragments can generate new epitope variants and suggest that there are far more possible epitopes than previously thought (Nature, 427:252-256, January 15, 2004).
|
|
|||||||||
|
|||||||||
|
