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In cell cycle, size matters
Email: Cathy Holding - cathyholding@aol.com News from The Scientist 2004, 5(1):20040825-01
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An active size-sensing mechanism may control the cell cycle in mammalian cells, according to a letter in Nature Cell Biology this week. A size threshold adjusts cell cycle length in the next cycle to ensure maintenance of a proper balance between growth and proliferation rates in various vertebrate cell types including human, mouse, and chicken erythroblasts and fibroblasts in vitro, Ernst Müllner and colleagues at the Department of Medical Biochemistry at the Vienna Biocenter found in their study.
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