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Inclusion bodies acquitted
Email: Maria W Anderson - manderson@the-scientist.com News from The Scientist 2004, 5(1):20041014-01
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Inclusion bodies play a protective, not pathogenic, role in Huntington disease, according to this week's Nature cover study by Steven Finkbeiner, from the Gladstone Institute of Neurological Disease. The paper contributes to an ongoing debate about the role of inclusion bodies—intracellular clumps of mutant huntingtin (Htt) protein—in the pathology of diseases like Huntington's and spinocerebellar ataxia.
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