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Epigenetics lives on in clones
Email: Melissa Phillips - mlphilli@u.washington.edu News from The Scientist 2005, 6(1):20050202-01
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A cloned Xenopus embryo overexpressed genes that were being actively transcribed in its parent cell at the time the nucleus was transferred, according to a study published in this week's PNAS. This suggests that the embryo "remembers" what type of cell its nucleus came from, according to study co-author John Gurdon. He and Ray K. Ng of the University of Cambridge report that genes specific to the cell type of a transferred nucleus are turned on in the wrong tissues of some cloned embryos at early stages of development.
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