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How mtDNA mutations cause aging
Email: Charles Q Choi - cqchoi@nasw.org News from The Scientist 2005, 6(1):20050715-02
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Mitochondrial DNA mutations appear to lead to aging by induced apoptosis and not by increased production of free radicals that lead to cellular damage as previously thought, scientists report in this week's Science. Tomas Prolla at the University of Wisconsin-Madison and colleagues found a rise in mtDNA mutations led to premature aging but not to increased levels of reactive oxygen species.
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