The Scientist : Tumor malignancy linked to rigidity [19/9/2005]

Email: Charles Choi - cqchoi@nasw.org
News from The Scientist 2005, 6(1):20050919-02

19 September 2005

Tissue rigidity might help promote tumor progression, scientists report today in this month's Cancer Cell. These findings help demonstrate how stiff surfaces can lead to malignant growth, and could help explain why continued culturing of normal cells for many passages on rigid plastic dishes often leads to spontaneous transformation, Don Ingber at Harvard Medical School, who did not participate in this study, told The Scientist.

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