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The Scientist
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cover story:
Tagged for Cleansing
New findings are showing that the ubiquitin system does a lot more than just mop up waste. Howard Hughes Medical Institute investigator MICHELE PAGANO and his colleagues have found that components of this elegant regulatory system also play a crucial role in cell death, circadian cycling, protein synthesis and other processes.
A Fading Field
Traditional taxonomists have become an endangered species, as biologists increasingly rely more on molecular tools and less on field work and morphological study. BOB GRANT asks: As this ancient field fades away, could its unique brand of knowledge disappear too? PLUS, check out two videos of scientists describing their struggles to attract students and funding (part 1, part 2).

Best Places to Work in Industry
Companies atop this year's survey provide their employees with a sense of security in an uncertain economic climate, reports TIA GHOSE. How does your company rank? See the top 30 companies, best big and small places to work, and profiles of some of this year’s success stories, including Pioneer Hi-Bred (#1 large company), Infinity Pharmaceuticals (#1 small company), and Alnylam (#6 small company).

For Shame, Merck and Elsevier
Everyone makes mistakes—it's how you handle them that matters. RICHARD GALLAGHER

Stimulus Application? Not Me
Just because there's extra money, doesn't mean it's easier to get. STEVEN WILEY

Experiments in Epidemiology
How honey bees could have helped control swine flu. PHILIP T. STARKS & NOAH WILSON-RICH

Hot Paper: Over the Brainbow
Two years after the colorful project made a splash, most researchers are still relying on older techniques to map neural linkages. TIA GHOSE
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  Friending Pharma
Tips from three kinds of collaborations with industry

Do not disturb
Do iPods make us worse (or better) scientists?

High life
Scientists find life teeming in one of the most unlikely places

Benching bases
How to do heavy computational lifting in genomes and transcriptomes

Is Murray hypoallergenic?
His owner—who paid $6000 for him—doesn’t think so

On the MAP
By charting the unknown territory of cellular signaling—including the M.O. of the oncogene Ras—Chris Marshall has transformed the landscape of cancer research
Year of the compound
Will a novel codevelopment model open up China's drug discovery platform?
A doyen steps down
Thanks, in part, to Audrey Evans and her 60 years in science, today about 75% of kids with neuroblastoma survive
Led by the nose
The challenge: Get the dog’s sense of smell without the dog
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