CONTENTS

February 2006

FEATURES
Submissions are up, reviewers are overtaxed, and authors are lodging complaint after complaint about the process at top-tier journals. What's wrong with peer review?
By Alison McCook
Truth or Myth?
What About Fast-Track?
Success has been mingled with failure; a few technical modifications could make the method safer
By Alain Fischer and Marina Cavazzana-Calvo
7 Steps to Better Gene Therapy
The five years since the draft of the human genome was published have been productive but bumpy. What will the next five be like?
By Victor K. McElheny
Where Are We Now?
Delivering on the Dream
Teaching a New Language
How do you convince people to do what's in their best interest?
By The McDonnell Social Norms Group
Barriers to Adoption
College Drinking: Norms vs. Perceptions
ALSO THIS MONTH

TAKING ON PEER REVIEW

Authors may need to take some of the blame for what ails the system
By Richard Gallagher

MAIL

Will cancer immunotherapy fail?; The science of a banned pesticide

THE AGENDA

Darwin turns 197; Book to note; Don't believe it; The Visa Master Card

LUGE AND THE LAB

By Ishani Ganguli

NATURE HAS WIKIPEDIA IN ITS CITES

By Stuart Blackman

OMEGA-3s SANS FISH

By Stephen Pincock

GROWING POT FOR SCIENCE

By Ishani Ganguli

ELECTRON MICROSCOPY ON THE RUNWAY

By Michael D. O'Neill

TIME TO ABANDON THE THREE Rs

Submitting to "refinement, reduction, and replacement" risks the future of animal research
By Stuart W.G. Derbyshire

LIES, DAMN LIES...
AND SCIENTIFIC MISCONDUCT

It's time for a revolution in the ethics of research
By Glenn McGee

THE HIDDEN DANGERS OF FUNDAMENTALISM

A connection exists between disease outbreaks and extreme religious practice
By Jack Woodall

THE AGE OF SENESCENCE

Judy Campisi's work on cancer may reveal the secrets of (not) getting older
By Karen Hopkin

GENOMICS GOES TO THE DOGS

How first-generation pooch genomes presaged things to come
By Aileen Constans

NAILING THE LacY MECHANISM

By Ishani Ganguli

A Q-DOT BIOPSY?

By Aileen Constans

PS II UNVEILED

By Aileen Constans

PAPERS TO WATCH

 

ENDOCYTOSIS IN REAL TIME

 

ENDOSYMBIONT AIDS PATHOGENIC FUNGI

 

SCIENTIST TO WATCH

Sangeeta Bhatia Looks at Life's Architecture
By Steve Nadis

MY OWN PRIVATE GENOME

So you want your own genome sequenced. What's that going to cost?
By Jeffrey M. Perkel

A PRACTICAL GUIDE TO THE HAPMAP

Here are five tips to getting the most out of your next gene-association study
By Aileen Constans

HOW IT WORKS

Genotyping Microarrays
By Aileen Constans

MARRYING DRUGS TO DIAGNOSTICS

Companies and regulators see codevelopment as the best medicine
By Randall C. Willis

MEETING HALFWAY?

FDA and industry prepare to revisit the costs and benefits of interaction during the drug approval process
By Ishani Ganguli

READING BETWEEN THE LINES

How to judge people by their resumes
By Ruedi Sandmeier
The Good, the Bad (and the Ugly)
10 items to keep in mind when scanning a resume

FUNDING A START-UP?
FRIENDS LEAD THE WAY

By Ted Agres

XX MARKS THE SPOT

By Ned Stafford

FOUNDATIONS

The First Automated DNA Sequencer
By Brendan Maher