April 2007

BIOSENSE OR BIONONSENSE? Years of development and hundreds of millions of dollars later, what has the CDC's syndromic surveillance program accomplished?	RELATED: Syndromic surveillance in California
GROWING A NEW ANTIDEPRESSANT Nine years ago, Rusty Gage shattered a neuroscience dogma when he showed that human brains give birth to new neurons. Today, a company is eager to take those findings to the clinic.	RELATED: A harsh decree: Everything may die, nothing may be regenerated The paper trail Video: 3-D Neurogenesis
THE VACCINE CONUNDRUM A highly effective treatment strategy is being ignored by many companies and investors. What can be done to boost funding?	RELATED: Why vaccines are a good investment
SPRING BOOKS SPECIAL From stem cells to wild trees and evolution to CSI, a recent crop of books has something to say about scientific conflicts, conquests and controversies.	RELATED: Christopher Thomas Scott reviews a trio of new stem cell books Jennifer Rohn reviews Lynn Margulis’ Luminous Fish Brendan Maher examines faith, Darwin, and Intelligent Design Andrea Gawrylewski reviews Richard Preston’s The Wild Trees Newamul Khan takes on Saxons, Vikings, and Celts by Bryan Sykes Faith McLellan writes on Michael J. Sandel’s Case Against Perfection Katharine Ramsland picks her way through books about bodies Wendy Chao test drives the latest lab manuals Reviews in Brief

Mail

Hormones in milk; Avoiding conflict in the lab; Peering into Carnegie; Pharma goes Hollywood; ‘Shroom science

EDITORIAL

Companies, you’re on notice. Want press coverage? Here’s what to do – and what not to do.
RICHARD GALLAGHER

COLUMNS

Socrates 2.0 Can bioethics be taught on the Internet?
BY GLENN McGEE

Disease control by decree How not to deal with epidemics.
JACK WOODALL

Notebook

The Agenda; Scooped by a blog; The whirling fish kill; (Slideshow: The whirling fish kill); The sniffling sheep;Biotech horsekeepers; A war against war metaphors

FOUNDATIONS

Fifty years with interferons

PROFILES

The Chromosome Queen
Nancy Kleckner, who grew up with molecular genetics, has answered some of the field's most important questions.
KAREN HOPKIN

The Moose in the Room
Centocor CEO Neal Fowler learned valuable lessons in sales about straight talk that he hopes will help his company through uncertain times. Just don't ask him about potential layoffs.
JEFF MINERD

Scientist to Watch Rachel Wilson: Death defying
How a 10-year project thought to be doomed to failure revealed what endocannabinoids do in the brain.
CATHY TRAN

THE LITERATURE

Hot papers: ANDREA GAWRYLEWSKI on how CyPD knockout mice reveal a path to necrosis

Fat mice and Clock mutants

Oncogenes in moles

A new design on an old drug

Papers to watch

Paper to watch: Locust navigation

Paper to watch: Hidden Markov genomics

LAB TOOLS

An RNAi rogue's gallery How to size up the available libraries for high throughput screening in mammalian cells.
ALLA KATSNELSON

How it works: Automated pipettor
BRENDAN MAHER

CAREERS

Bringing cancer science to the bedside NIH is investing millions of dollars in translational cancer research. How can you get involved?
EDYTA ZIELINSKA