CONTENTS
May 2008
A few years ago, Alan Schneyer was running a lab that was producing interesting results in the field of reproductive endocrinology. Then he became one of the growing number of scientists who are denied renewals of their NIH grants. His staff slowly trickled out, his resources dwindled, and he eventually moved his lab to a small institute that's a 90-minute drive from his home. ALISON McCOOK tells his story. |
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When you're a short drive (weather permitting) to a synchrotron, you can do some interesting science. STEPHEN PINCOCK visits the Swiss Federal Institute of Technology (ETH) to watch its structural biologists tackle some of the field's most intricate and risky projects. |
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As a 29-year-old physicist, ANTOINE VAN OIJEN sat among 18- and 19-year-old undergraduates to learn the basics of molecular biology. He has already developed tools to watch energy jump within a photosynthetic protein and a virus particle infiltrate a cell surface - leading, perhaps, to better antiviral drugs. |
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EDITORIAL The Importance of a Plan B Even when the source of your salary is the government, it's not a guarantee. COLUMNS Hypothesis-Free? No Such Thing Even so-called "discovery-driven research" needs a hypothesis to make any sense. OPINION When Collaborations Compete What to do when you know two scientists are competing with each other, and they don't. Notebook The Agenda; Speciation's roots?; Slideshow: Crossing Arabidopsis Strains ; New look at old wounds; Brain quakes; A life behind life science; The media monitor FOUNDATIONS Wistar Melanoma Lines, 1977-present PROFILES Switched on Science James Collins has shifted gears from medical engineering to gene switches, and won a MacArthur grant along the way. Scientist to Watch:Howard Hang An immunologist's chemist BIOBUSINESS: Dandruff Genomics At Procter & Gamble, Thomas Dawson has led the charge to put more biology in every bottle of shampoo. Plus a slideshow on Procter & Gamble's work on dandruff genomics. THE LITERATURE Hot paper: Opposing Translations Two structures of the ribosome ignite debate and discovery in structural biology. Hot paper in Synthetic Biology: Bacteria’s bare necessities Hot paper in Virology: Evading immunity Hot paper in Drug Development: Bacteria killers Citation Classic: 50 Years Ago in Biochemistry Demystifying a Key Biochemical Reaction. LAB TOOLS Sweet Attachments Isolating and detecting glycosylated proteins. Plus, researchers describe their preferred methods for detecting glycoproteins: Phospho-match; Sugar ID; Polyclonal; Needle in a haystack; and Classic chemistry. And Off-the-shelf glycoprotein detection methods CAREERS Getting on board How serving on a scientific advisory board can serve you. SPECIAL ADVERTISING SECTION
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