CONTENTS
March 2009
If you want to study how environmental change affects organisms system-wide, you can forget about E. coli, which is accustomed to the uniform zone of the gut. Instead, scientists are turning their gaze to a bacterium that thrives both with and without oxygen, another that photosynthesizes by day and fixes nitrogen by night, and an extremophile that loves salt. As ELIE DOLGIN demonstrates, some peculiar microorganisms are showing systems biology can color in what's missing from models of molecular responses to environmental change. |
Related Articles Systems Biology Weathers the Storm |
Ever wish you could forget something? Today,
there are drugs available that can act on the
molecular and cellular basis of emotion and
memory to disrupt long-term memories, which
early evidence shows can help patients with
post traumatic stress disorder. JOSEPH LEDOUX
of New York University explains how. |
Related Articles |
International postdocs often take on challenges
that go beyond the lab. JENNIFER EVANS finds
out how this year's top institutions help foreign
fellows adjust to their new lives. |
Related Articles Whitehead comes into the spotlight Ranking Tables: Top International Institutions Additional Articles: Best Places to Work 2008: Industry |
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EDITORIAL The People's Lab
Amateurs have the freedom to experiment and innovate—watch out for their impact. COLUMNS The Problem of Perception Your interpretation of results depends
on more than just the results. The Economic Stimulus and Science A fixed percentage of a country's
GDP should be committed to
research. Notebook A matter of chow; Tooth ferrying; Parroting virus; Paleo-ethno-what?; Frankenfish FOUNDATIONS Alzheimer's Pathology, circa 1906 PROFILES Burning Chromatin at Both Ends Shiv Grewal has seen both late
nights and early mornings in the
lab—and connections between seemingly
disparate elements that other
molecular biologists might miss. Scientist to Watch: Ed Boyden The brain engineer BIOBUSINESS: Personalized Meddling Frankie Trull wants to sell your company
to Congress. THE LITERATURE Hot paper: Damage Control Researchers unlock a treasure trove of information about how cells sense and respond to DNA damage. Hot paper in Microbiology: Cracking CRISPR Hot paper in Evolutionary Biology: Improved invaders Hot paper in Plant Development: JAZ conducting LAB TOOLS Mass Spectacle Making the most of mass spectrometry
imaging; Protein challenge; Bedside Imaging; Easy living tissue ; 3D drilling; Old hardware, new uses CAREERS Fixing Fraud Tips for preventing research misconduct
and maintaining the integrity of
your research. |