CONTENTS

September 2009

Cassava with extra beta-carotene, carrots with more calcium, tomatoes richer in antioxidants— scientists have genetically engineered several biofortified food plants to tackle a scourge of developing countries, micronutrient malnutrition. The crops have yet to cover wide swaths of land, but, as BOB GRANT writes, that may be about to change.

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Aid for Poverty—and Pudding

Implementing Change

Africa needs basic science

Every year in the US, hundreds of thousands of miscarriages occur. But more than half of couples who experience recurrent miscarriage never learn why it happens. A newly found cause of miscarriage raises hopes for treatment, such as a drug already on the market for other indications, identified by researcher GUILLERMINA GIRARDI. But when will clinical trials take place?

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A Complementary Pathway

A mouse with postpartum depression?

Statins stop tumor cells

How does your salary compare? Plus, an analysis of the financial state of the field by JEF AKST, who found that institutions are keeping salaries static in the depressed economy by cutting jobs, forcing furloughs, and making changes to infrastructure.

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Finding New Money

Stimulus Application? Not Me

Retiring from Science

Scoring on Sabbaticals

Comparison Charts and Data

State-by-State Salaries

Downloadable PDF's

CONTRIBUTORS

MAIL

EDITORIAL

Aid for Poverty—and Pudding
New technology for curbing nutrient deficiency is being cruelly held up.
RICHARD GALLAGHER

COLUMN

Bring Back Reprint Requests
I miss the instant feedback from the larger scientific community on my papers.
STEVEN WILEY

OPINION

NIH R01s: No Longer the Best Science
Funding preferences penalize senior investigators, lower the quality of science.
LES COSTELLO

NOTEBOOK

Wild-type work
Next top model
Military minds
Science, rah rah
Mini-mass spec

FOUNDATIONS

C. elegans Physical Map, circa 1989
ELIE DOLGIN

PROFILE

Crossing Over
Following his instinct, Douglas Bishop has tracked the mechanisms behind mismatch repair and homologous recombination.
KAREN HOPKIN

SCIENTIST TO WATCH

J. Christopher Love
The Nanoimmunologist
ELIE DOLGIN

BIO BUSINESS

Dimmer-switch Drugs
A growing number of companies are exploring molecules that modulate targets, rather than just switching them on or off.
MEGAN SCUDELLARI

THE LITERATURE

Transcription Surprise
A strange finding sparks a closer look at this fundamental process.
ALLA KATSNELSON

Hot paper in Environmental Genomics: Sequencing soil
ELIE DOLGIN

Hot paper in Animal Behavior: When the Lévy breaks
ELIE DOLGIN

Hot paper in Immunology: Directing degradation
EDYTA ZIELINSKA

LAB TOOLS

Surpassing the Law of Averages
How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells
JEFFREY M. PERKEL

CAREERS

Talking Yourself Up
How to score points on an interview and what to do after it's over
JEF AKST