CONTENTS

January 2010

Evolution, by its very nature, is a dynamic process. Now, some evolutionary biologists say that the codification of evolutionary processes should formally incorporate what scientists have recently learned about genomics, molecular biology, developmental biology, and systems biology. But is such an official change necessary? BOB GRANT presents the new, proposed rules of evolutionary theory.

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Video: Evolution Evolving

Last Act

Do Complex Orgs Evolve More Slowly?

Meet the new blockbusters: After a rocky period, the vaccine sector is now thriving, MEGAN SCUDELLARI reports, thanks to new technologies, legislation, investment in the developing world, and a moneymaking reputation. In short, vaccines could represent the booster shot the pharmaceutical industry needs.

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A Cancer Vaccine -- That Works?

Modest HIV Protection Confirmed

Diverting a Diet Drug

Whether it's powering through the cytoplasm leaving a trail of polymerized actin, or storing the code for RNA transcripts on the wrong side of DNA, Listeria makes up its own rules for survival, according to PASCALE COSSART, an HHMI international research scholar at the Pasteur Institute

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Video: Intracellular Listeria Infection

Antiviral Response Promotes Bacterial Infection

The Force Behind Biomechanics

CONTRIBUTORS

MAIL

EDITORIAL

The Last Act
My final editorial.
RICHARD GALLAGHER

COLUMN

Mind Your Manners
We need to treat each other with respect, or all of science will suffer.
STEVEN WILEY

OPINION

Outreach Going Wrong?
When we talk nano to the public, we are leaving behind key audiences.
ELIZABETH A. CORLEY AND DIETRAM A. SCHEUFELE

NOTEBOOK

A pipeline rerouted
The successful squish
Research remand
Desperately seeking seahorses
A pioneer's perils

FOUNDATIONS

Transfer RNA Model, 1975
DEBORAH DOUGLAS

SCIENTIST TO WATCH

Tara Kieffer
From helix to hepatitis
KATHERINE BAGLEY

BIO BUSINESS

Home-base Biotech
African and international efforts are boosting the continent's biotech industry—for now.
KATHERINE BAGLEY

THE LITERATURE

Tricky T Cells
A new lymphocyte behind autoimmunity has created feverish excitement—and raised as many questions as it answers.
KATHERINE BAGLEY

Hot paper in Cell Biology: Hindering HIV
JEF AKST

Hot paper in Microbiology: Baby bellies
VICTORIA STERN

Hot paper in Evolutionary Biology: Moss makeup
KATHERINE BAGLEY

LAB TOOLS

Automate to Market
How to make your dreams of lab automation a reality.
KELLY RAE CHI

CAREERS

Power Couples
Three highly productive couples give advice on how to balance life at home and in the lab.
VICTORIA STERN