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Glued to Another Tube
Alexander Grimwade | Apr 20, 2003 | 1 min read
 Click for larger version (45K) A past Snapshot showed that more than 80% of scientists regularly watch television. We surveyed 317 readers to find out what they turned on. Not surprisingly in these difficult times, more than 80% frequently watch news and news programs. A solid 68% click on science documentaries, followed by more escapist fare--movies and comedy programs. Our readers' favorite regularly watched program, and most preferred all-time show, is CSI: Crime Scene Investigation.
Barbara McClintock, On Her Own
The Scientist Staff | Apr 20, 2003 | 1 min read
Foundations | Barbara McClintock, On Her Own  Click for larger version (49K) Geneticist Barbara McClintock, since her death in 1992, has become a feminist hero. She held steady in the male-dominated world of science, earning her first award in 1947 and culminating her career in 1982 with the Nobel Prize. Her observations and discoveries laid the groundwork for modern genetics research. Her theory that the genome constantly changes and regulates itself, derided in her time as being outl
Good Vibrations; Annotation Illustration; Speedy Sequencing
Jeffrey Perkel | Apr 6, 2003 | 3 min read
Gadget Watch | Good Vibrations Courtesy of Bel-Art Products Who hasn't experienced this frustration: When measuring out a minute quantity of a precious reagent in the microgram balance, your hand slips, and whoops! You've just dumped--and possibly lost--way more powder than you need. The Quaver® nonmotorized vibrating spatula and its nimbler sibling, the Quaverette®, could make such problems things of the past. Manufactured by Bel-Art Products (www.bel-art.com) of Pequannock, NJ, t
DNA Base Pairs, and Erwin Chargaff
The Scientist Staff | Apr 6, 2003 | 1 min read
Foundations | DNA Base Pairs, and Erwin Chargaff  Click for larger version (32K) Erwin Chargaff's groundbreaking research, which showed that DNA base pairs had a complementary relationship, laid the foundation for James Watson's and Francis Crick's DNA model. When word spread that Watson and Crick had solved the structure, Chargaff wrote to Maurice Wilkins, who worked with Rosalind Franklin at Kings' College, London--and who later received the Nobel Prize, along with Watson and Crick.
Married to Science
Alexander Grimwade | Apr 6, 2003 | 1 min read
Snapshot | Married to Science  Click for larger version (40K) And some even like it Of the 308 surveyed readers of The Scientist who are married or in long-term relationships, 36% have scientists as partners, 8% working together in the lab. More than 100 respondents commented on such an arrangement--most are enthusiastic, or at least content with their lot. Most who work with their scientist partners extol the benefits of cooperation and mutual understanding. Said one: "It's great to
Little Green Bacteria
Martin Chalfie | Sep 7, 2003 | 2 min read
Foundations | Little Green Bacteria Click for larger version of notes (68K) When I first heard Paul Brehm [then at Tufts University] mention green fluorescent protein at a seminar in the late 1980s, I got excited; I knew it had the potential to be an expression marker. I talked with Doug Prasher, who was trying to isolate a gfp cDNA, and we promised to keep in touch. But we lost track of each other after I married and went to do my sabbatical at my wife's university. In September 1992, I
Scientist by Nature ... and Nurture
Alexander Grimwade | Nov 2, 2003 | 2 min read
Click for larger version of survey graph (22K) Some 425 readers told us about the influences that guided them to become scientists; they cited an average of three influential factors. By far the most important, according to 70% of our respondents, was innate curiosity. "I cannot help but poke things until I find out how they work," says one. Another notes, "I have known since I was a toddler that I would become a biologist." Secondary school teachers (46%), parents (46%), and college teacher
Evil Science
The Scientist Staff | Jun 29, 2003 | 2 min read
Foundations | Evil Science Click for larger version (39K) Few events signify science gone awry more than the Tuskegee experiments. Started in 1932 to study the effects of untreated syphilis in 399 black men, the scientific rationale for the work became inconsequential by the late 1930s, when it was proven that the symptoms could be treated with heavy-metal therapy. Yet bureaucratic inertia compelled its continuation. In 1943, the morally questionable descended to the intentionally harmful
The Genesis of Prozac
The Scientist Staff | Jun 1, 2003 | 2 min read
Foundations | The Genesis of Prozac  Click for larger version (71K) Fifty-plus years ago, Julius Axelrod and his colleagues discovered the phenomenona of neurotransmitter inactivation by reuptake into the nerve terminal, a finding that led to the development of antidepressant drugs. By increasing the neurotransmitter amount in the synaptic cleft, this allowed greater amounts of the neurotransmitter to act on postsynaptic receptors more intensely. "This is an example of basic important
'Unlimited in its Implications...'
The Scientist Staff | May 18, 2003 | 2 min read
Foundations | 'Unlimited in its Implications...'  Click for larger version (30K) One cold night in 1945, a Columbia University medical school student named Joshua Lederberg read Oswald Avery's 1944 landmark paper that identified deoxyribonucleic acid as the chemical that carries genetic information. Lederberg wrote his immediate reactions in a diary entry the next day: "I had the evening all to myself, and particularly the excruciating pleasure of reading Avery ... Terrific and unlimi

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