Latest

Image of <em >Candida albicans</em> fungus.

A Fungus Plays Tug-of-war for Metal Ions

Laura Tran, PhD | Sep 14, 2023 | 3 min read

In the fight between hosts and fungal pathogens, scientists discovered how withholding manganese can cripple Candida albicans.

2024 Breakthrough Prizes in Life Sciences

Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

The Scientist's Journal Club: Transcriptomics

The Scientist’s Creative Services Team | 2 min read

Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.

Professor Sir Ian Wilmut with Dolly the sheep

Ian Wilmut, Famed Scientist Who Led the Creation of Dolly the Sheep, Died at 79

Shelby Bradford, PhD | Sep 12, 2023 | 3 min read

Knighted in 2008, Sir Ian Wilmut revolutionized the field of cloning, stem cell research, and regenerative medicine.

An image of lung tissue acquired using a MALDI imaging mass spectrometer.

Glycogen Metabolism May Play a Key Role in Pulmonary Fibrosis

Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read

Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development.

3D rendered illustration of the human gastrointestinal tract with an inset close up of the epithelium.

Exploring Preclinical Models for Inflammatory Bowel Disease

The Scientist’s Creative Services Team and Altis BioSystems | 4 min read

Learn how epithelial monolayer models help researchers discover effective therapies and biomarkers for inflammatory bowel diseases.

Carolyn Bertozzi working in the laboratory with postdoctoral scholar Ula Gerling-Driessen

Trimming Undruggable Cancer Targets

Deanna MacNeil, PhD | Sep 13, 2023 | 4 min read

Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.

Close up on eyes of mother and daughter faces next to one another

A Long and Unhealthy Life?

Aparna Nathan, PhD | Sep 13, 2023 | 3 min read

A new mouse model shows that the Myc protein has complex effects on aging and cancer.

How to Speed Up Cell Therapy Development Processes

The Scientist’s Creative Services Team | 1 min read

In this webinar, Patrick Schmidt will explore how to streamline CAR T cell product manufacturing processes for immunotherapy.

Image of spatial transcriptomic spots superimposed onto a stained tissue section.

Poor Cancer Prognosis Associated with a Transcriptional Signature

Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read

Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types.

Woman smiling at the camera working out on a blue yoga mat.

Keeping Older Muscles Strong

Hannah Thomasy, PhD, Drug Discovery News | Sep 5, 2023 | 5 min read

From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.

New Strategies for Cancer Immunotherapy

The Scientist’s Creative Services Team | 1 min read

An expert panel will discuss the interplay between cancer and the immune system, and how researchers develop immunotherapies and other immune-supporting strategies against cancer.

Colorful blue and pink low poly side view human brain illustration with connection dots isolated on bright blue background

Cancer Cells Need Fatty Acids to Survive in the Brain

Danielle Gerhard, PhD, Drug Discovery News | Aug 30, 2023 | 3 min read

Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.

The illustration shows floating chromosomes with a Y-shaped chromosome in the foreground.

Closing the Gaps in the Human Genome: Why Y Was the Final Hurdle

Kamal Nahas, PhD | Aug 28, 2023 | 4 min read

For two decades, scientists struggled to fully sequence the Y chromosome. Finally, researchers have mapped its full length thanks to recent advances in sequencing technology.