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3D rendered image showing enhanced scanning electron micrograph of cancer cells.
Turning Off Metastasis in Breast Cancer
Nathan Ni, PhD | Feb 13, 2024 | 4 min read
An on-off enzyme switch controls metastasis in mice. 
Epigenetic Influences and Mechanisms in Cancer
Epigenetic Influences and Mechanisms in Cancer
The Scientist Staff | 1 min read
In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Twisted DNA Increases CRISPR Off-target Effects
Shelby Bradford, PhD | Feb 8, 2024 | 4 min read
Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.
From the Expert: Click Chemistry and Bioorthogonal Applications
From the Expert: Click Chemistry and Bioorthogonal Applications
The Scientist Staff | 1 min read
Carolyn Bertozzi discusses her recent work on targeted degradation therapies that rely on bioorthogonal chemistry.
3D illustration of greenish-brown rod-shaped bacteria.
A Novel Molecule to Tackle Drug-Resistant Bugs
Aparna Nathan, PhD | Feb 12, 2024 | 4 min read
A new antibiotic is the first to block a critical transport mechanism in drug-resistant bacteria.
3D rendered anatomy illustration of a fetus in a womb.
Placental Gene Expression Hints at Preterm Birth
Deanna MacNeil, PhD | Feb 12, 2024 | 4 min read
Researchers mapped out cellular changes in the maternal-fetal interface to uncover term and preterm labor complexities.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Shielding From Allergies: It’s Not Just About Microbes
Mariella Bodemeier Loayza Careaga, PhD | Feb 7, 2024 | 4 min read
Clean and dirty mice respond similarly to allergens, challenging the idea that reduced microbial exposure is the primary cause behind the uptick in allergies.
Novelty Activates a Long Noncoding RNA for Spatial Learning in Mice
Shelby Bradford, PhD | Feb 6, 2024 | 4 min read
Genes activated in new environments include those used during development.
Mitigating Biopharmaceutical Impurities in Monoclonal Antibody Therapeutic Manufacturing
Host Cell Protein and Impurity Risk Mitigation in Monoclonal Antibody Therapeutic Manufacturing
The Scientist Staff | 1 min read
In this webinar, Andrew Hamilton and Joe Hirano will explore how to detect and remove host cell proteins and other impurities during biologics manufacturing.
Back Pain Explained
Rachael Moeller Gorman | Feb 5, 2024 | 4 min read
Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.
Avoiding Gene Editing’s Unintended Consequences
Tanvir Khan, PhD | Feb 2, 2024 | 4 min read
CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.
Building Broader B Cell Diversity for Better Monoclonal Antibody Discovery<br ><br>
Building Broader B Cell Diversity for Better Monoclonal Antibody Discovery
The Scientist Staff | 1 min read
In this webinar, Vincent Pai will discuss how the latest automated single B cell functional screening technology helps researchers meet the demands for new monoclonal antibody candidates.
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