News & Opinion

Covering the life sciences inside and out

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

Three new strategies for using DNA to generate large, self-assembling shapes create everything from a nanoscale teddy bear to a nanoscale Mona Lisa.

The Nutshell

Daily News Roundup

A provision to tax tuition waivers was dropped during the reconciliation process.

The first industry-sponsored CRISPR therapy is slated to be tested in humans in 2018.

The new test could improve upon two current methods to diagnose tuberculosis—a skin test or culturing bacteria from saliva, both of which take days.

Marie Claire speaks with researchers who’d reported abuse in studies of harassment in the field.

Current Issue

December 2017

Issue Cover: The Embryo's Secrets Revealed

From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

Growing evidence points to a once-habitable world—and recent findings suggest that life could exist on Mars today.

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

Multimedia

Video, Slideshows, Infographics

Try your hand at a sciency brain teaser.

See how well you did.

The Marketplace

Sponsored Product Updates

Sequencing cell-free DNA (cfDNA) fragments, a biomarker used to detect and treat cancer via a liquid biopsy, needs an optimal DNA concentration during flow-cell loading. 

Handling brain tissue can be very challenging, especially when attempting to employ free-floating IHC techniques. A non-biotin, one-step detection system can yield better results than traditional biotin-avidin/streptavidin methods while remaining suitable for multiplex IHC. Find out more with this application note from Enzo Life Sciences!

ProImmune, a leader in services for understanding immune responses, today announced the introduction of MutaMap™, a new high-throughput assay service for understanding the impact of point mutations on protein therapeutic activity, including monoclonal antibodies.

At Booth 534 Lonza will showcase how its automated QC testing solutions and Nucleofector™ Devices can increase efficiency and throughput in the drug development process. 

Washing cells for flow cytometry can potentially alter cell biology. With this information package from Curiox BioSystems, find out more about how DA-Cell automated methods use laminar flow washing and a unique SBS-standard 96-well plate to remove excess fluorescent marker without stressing the cells.

The Anti di-Ubiquitin K6 and K33 Affimers from Avacta are a unique range of binders, with no antibody or aptamer equivalents.

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Featured Comment

Sad day for the research community on cell division. What a disservice to science.

Sonia Rossell, commenting on The Scientist's Facebook page about renowned Univeristy of Tokyo cell biologist Yoshinori Watanabe being found guilty of manipulating images in five research papers from his lab.

Investigation Finds Cell Biologist Guilty of Misconduct
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