Visualizing neuronal connections is highly important for understanding brain organization and pathophysiology. However, this data has historically been obtained through invasive and often terminal procedures. Technological advances have permitted the development of a new era of neuroanatomical tracing techniques.
In this eBook from Gilson, learn the basics of HPLC, the difference between analytical and preparative HPLC, the pros and cons of different preparative HPLC techniques, and the wide range of applications of HPLC!
Microfluidic modulation spectroscopy (MMS) analysis combines laser spectroscopy, microfluidics, and signal processing to provide direct, label free measurements, giving researchers information on higher order structure, aggregate formation, protein stability, and concentration. Download this white paper from RedShiftBio to learn more about MMS!
Isotype control antibodies are essential negative controls for in vivo studies and can play an important role in standard immunoassays. Download this white paper from Crown Bioscience to learn why isotype controls are important, how to select them, and why they should not be substituted for other alternatives (PBS, secondary only, or polyclonal pools).
Unlike traditional lipophilic membrane dyes like DiO and DiI, CellBrite™ Fix dyes are fluorogenic lipophilic dyes that covalently bind the surface of live cells. The staining is simple, rapid, and much more uniform than other membrane dyes. Most importantly, surface staining is retained after fixation and permeabilization for immunofluorescence or other co-staining.
A rapid and inexpensive fluorescence method for screening conditions that affect protein thermal stability, such as protein mutations, ligand binding, and buffer formulations (like pH, salts, detergents, and other additives).