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tag 25 years cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Molecular Biology
The Scientist Staff | Mar 15, 1992 | 1 min read
T.J. Schall, M. Lewis, K.J. Koller, A. Lee, G.C. Rice, G.H.W. Wong, T. Gatanoga, et al., "Molecular cloning and expression of a receptor for human tumor necrosis factor," Cell, 61:361-70, 1990. Thomas Schall (Genentech Inc., South San Francisco, Calif.): "The biological effects of the protein known as tumor necrosis factor (TNF) have puzzled inves- tigators for years. Though binding studies have revealed that virtually all mammalian cells possess TNF receptors, the molecule's biological activit
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
danielle gerhard
Meet the Team: Danielle Gerhard, PhD
Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read
After years in the lab, Danielle Gerhard put down the pipette and picked up the pen to follow her passion for storytelling.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Advancing Drug Discovery by Employing Synthetic Biology Tools
Advancing Drug Discovery by Employing Synthetic Biology Tools
The Scientist | Oct 18, 2023 | 1 min read
In this webinar, learn about the origins of artificial gene circuits and how researchers currently use synthetic biology strategies to uncover new drugs. 
Microscopic Bowls Uncover the Secrets of Protein Secretions
Rebecca Roberts, PhD | Jan 30, 2024 | 4 min read
Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

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