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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: Explaining Elephants’ Cancer Resistance

Explaining Elephants’ Cancer Resistance

By | October 13, 2015

Two studies reveal that the giant mammals have dozens of extra copies of a cancer-preventing gene.

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: An Obesity-Cancer Link?

An Obesity-Cancer Link?

By | November 22, 2011

Why obese individual are more likely to get cancer could be partly explained by a gene that activates both pathways.

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image: MicroRNAs Prevent Cell Reprogramming

MicroRNAs Prevent Cell Reprogramming

By | October 24, 2011

A group of microRNAs can inhibit the formation of induced pluripotent stem cells, and may provide a target for more efficient reprogramming of somatic cells.

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image: The Axis of Aging

The Axis of Aging

By | June 14, 2011

Editor's choice in developmental biology

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image: Top 7 in molecular biology

Top 7 in molecular biology

By | June 14, 2011

A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.

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