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tag mrna neuroscience developmental biology evolution disease medicine

Top 7 in developmental biology
Bob Grant | Dec 17, 2010 | 3 min read
A snapshot of the most highly ranked articles in developmental biology, from Faculty of 1000
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Michelle Gray Tracks Huntington’s in Different Brain Cells
Amanda Heidt | Oct 1, 2020 | 3 min read
The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease’s initiation and progression.
Papers to Watch
The Scientist Staff | Mar 1, 2006 | 1 min read
K.K. Farh et al., "The Widespread Impact of Mammalian microRNAs on mRNA repression and evolution," Science, 310:1817-21, Dec. 16, 2005.Expression of mRNA carrying the conserved 7 nt sites matching microRNAs can be strong at developmental stages before microRNA expression but is reduced at a later stage. Genes preferentially expressed at the same time and place as microRNAs have evolved to avoid sites matching the miRNAs by adopting non-conserved sites.Fritz EcksteinMax Planck I
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Prenatal Exposure to Cannabis Affects the Developing Brain
Andrew Scheyer | Jan 1, 2019 | 10+ min read
Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention.

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