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tag mutations immunology ecology culture cell molecular biology
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
One Protein to Rule Them All
Shelby Bradford, PhD
| Feb 28, 2024
| 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD,
Spectrum
| Jan 26, 2023
| 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD
| Aug 31, 2022
| 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Monitoring Mutations with Microfluidics
Ruth Williams
| Mar 15, 2018
| 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD,
Drug Discovery News
| Aug 9, 2023
| 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky
| Mar 1, 2018
| 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD
| Sep 14, 2023
| 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Top 7 papers in cell biology
Jef Akst
| Dec 5, 2010
| 3 min read
Just in time for ASCB -- see the cell biology articles most highly ranked by F1000
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