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tag spinal cord injury genetics genomics microbiology culture

poliovirus nprv2 vaccine-derived polio reversion virulence 481a mutation genetic engineering
New Oral Polio Vaccine to Bypass Key Clinical Trials
Robert Fortner | Dec 17, 2019 | 6 min read
Health officials are rushing a genetically engineered product into the field to counter uncontained outbreaks of vaccine-derived polio.
The Future Looks Bright for Genetic Medicine
Ronald Crystal | Nov 21, 2004 | 5 min read
Today, gene therapy, genomics, and stem cell therapy are considered to be discrete fields of research.
Bespoke Stem Cells for Brain Disease
Nsikan Akpan | Jan 14, 2013 | 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.
Porcine Possibilities
Ricki Lewis | Oct 15, 2000 | 8 min read
Courtesy of PPL TherapeuticsA new generation of pigs. Headlines in late summer 2000 introduced long-awaited reports on pig cloning and retroviral transmission to mice, pig cells healing rat spinal cords, and a gaff by Dolly dad Ian Wilmut erroneously heralding halt of xenograft work at the Roslin Institute near Edinburgh, Scotland. So it seemed that the question of whether pigs can pass their retroviruses to humans might finally be on the road to resolution. Not quite. Pigs, as the purveyors o
New Era in Vaccine Development
Nadia Halim | Apr 16, 2000 | 6 min read
When all fails, try a new attack. That's exactly what researchers do when they use genome sequence data to develop vaccine candidates against the most difficult pathogenic adversaries. Recent efforts are revealing previously unknown microbial genes that may encode proteins important in triggering immunity. "Whole-genome data provides insight into all the features of [organisms] including access to virtually every single antigen that may provoke an immune response," explains Michael Gottlieb, pa
John Gearhart
Ricki Lewis | Dec 8, 2002 | 4 min read
File photo It is a sobering time for US stem cell researchers. Just days after a national election set the stage for the possible criminalization of embryonic stem cell research, a popular television program portrayed such cells incubating in patients in coma, ready to be used to treat a wealthy man's Parkinson disease. A video presented at the American Society for Human Genetics annual meeting in Baltimore a month earlier, however, told a very different story--this one real. The video showed
Those We Lost in 2017
Katarina Zimmer | Dec 27, 2017 | 10 min read
The scientific community bid farewell to a number of luminaries this year. 
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016 | 6 min read
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Week in Review: May 26–30
Tracy Vence | May 30, 2014 | 4 min read
Human proteome cataloged; island-separated crickets evolved silence; molecule shows promise for combatting coronaviruses; study replication etiquette; another call for STAP retraction
Reproductive Research Progresses Despite Restrictions
Sara Latta | Mar 1, 1998 | 8 min read
While the ethics of human cloning has dominated recent discussion of reproductive technologies, research involving human embryos has always been a political hot potato, entangled with the twin issues of abortion and the beginning of human life. Restrictive policies and negative public attitudes surrounding embryo research have made it increasingly difficult for the infertility research community to improve the success rates for assisted reproductive technologies. According to the Centers for Di

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