With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.

Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.

Biologists and mathematicians alike are finding their respective disciplines meeting at a very busy crossroads. The rapid advances in both fields, they say, have resulted in an explosion of information in the life sciences, and the creation of sophisticated mathematical tools for handling complicated biological systems. Studies over the entire range of the life sciences--from the molecular level (DNA and proteins) to entire organisms and ecosystems--benefit from insights derived from the mathe