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tag genetic variation genetics genomics microbiology culture

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Biology's Blockbuster: Visualizing Genetic Variations
Kelli Miller | Feb 17, 2002 | 3 min read
They say timing is everything, and when it comes to cancer that's especially true. Human cells grow and divide every 24 hours. But in a fraction of a second, an error can occur in the copying of the human genome. Spotting precisely when that error happens is key to understanding, and possibly preventing, the development of cancer. Traditional cell cycle analysis involves staining samples taken at random intervals. But these snapshots don't tell the whole story. To see exactly what takes place ea
Two hands cut and manipulate the genome surrounded by different organs of interest.
The Cre-loxP System: A Powerful Tool in the Genetic Toolbox
Laura Tran, PhD | Dec 4, 2023 | 9 min read
Standing at the cornerstone of genetic research, Cre-loxP recombination serves as molecular scissors for precisely manipulating the genome.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Photograph from 1918 influenza pandemic shows mask-wearing women holding stretchers at backs of ambulances in Saint Louis, Missouri.
100-Year-Old Lungs Yield Genetic Samples of 1918 Flu Viruses
Christie Wilcox, PhD | May 18, 2021 | 2 min read
Influenza RNA sequences from three sets of lungs preserved in formalin since 1918 provide new insights into the deadly pandemic.
Colored Genetic Code DNA Molecule Structure stock photo
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021 | 4 min read
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Can Genetics Explain Human Behavior?
Bill Sullivan | Sep 1, 2019 | 3 min read
The author of a new book about emerging concepts in human genetics considers the question.

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