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image: Detecting Protein Clumps

Detecting Protein Clumps

By Ruth Williams | February 1, 2018

A synthetic genetic tool called yTRAP allows high-throughput detection of protein aggregates in cells.  

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image: Image of the Day: When Cells Stop Cleaning

Image of the Day: When Cells Stop Cleaning

By The Scientist Staff | September 12, 2017

By stifling autophagy in the motor neurons of a mouse model of amyotrophic lateral sclerosis (ALS), scientists stem later-stage disease progression.

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image: Getting Back in Shape

Getting Back in Shape

By Karen Zusi | December 1, 2015

Contrary to years of research suggesting otherwise, most aggregated proteins regain their shape and functionality following heat shock.

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image: Neurodegeneration’s Spread

Neurodegeneration’s Spread

By Ashley P. Taylor | August 4, 2014

Researchers show that pathogenic protein aggregates that accumulate within neurons and are a hallmark of Huntington’s disease can propagate from cell to cell.

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image: Mea Culpa Retractions

Mea Culpa Retractions

By Kerry Grens | August 30, 2013

Researchers earn applause after recalling two papers containing misinterpreted findings.

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image: Prions Involved in Learning

Prions Involved in Learning

By Edyta Zielinska | February 15, 2013

Properly folded prions aid in normal brain development.

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image: Neil Bence: Manipulating Degradation

Neil Bence: Manipulating Degradation

By Kerry Grens | December 1, 2012

Senior Scientist, Millennium Pharmaceuticals: The Takeda Oncology Company Age: 39

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image: A New Model of Yeast Aging

A New Model of Yeast Aging

By Hannah Waters | November 23, 2011

New findings challenge long-held views about the mechanism yeast cells use to live forever.

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