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Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.

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image: “Retired” Mice Find New Life as Top Models for Autism

“Retired” Mice Find New Life as Top Models for Autism

By Jessica Wright | January 29, 2018

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.

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image: Study Raises Questions About Patient-Derived Xenografts

Study Raises Questions About Patient-Derived Xenografts

By Ashley P. Taylor | October 10, 2017

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

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image: Image of the Day: Fish Avatars for Cancer

Image of the Day: Fish Avatars for Cancer

By The Scientist Staff | September 11, 2017

Zebrafish larvae transplanted with patients’ tumors respond as their human donors do to chemotherapy.

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image: Zebrafish Embryos Survive Deep Freeze and Quick Thaw

Zebrafish Embryos Survive Deep Freeze and Quick Thaw

By Ashley Yeager | July 28, 2017

In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.

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image: First Genetic Screen of Pigs Using ENU

First Genetic Screen of Pigs Using ENU

By Ashley Yeager | July 14, 2017

Using the mutagenic chemical N-ethyl-N-nitrosourea, researchers confirm the role of a gene in a piglet deformity and identify potential models for human diseases. 

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The lungs of extremely premature lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers report.

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While studying the progression of healthy cells into cancerous ones, researchers discover a way to engraft human blood cells into animals.

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image: Opinion: Canine Models for Alzheimer’s

Opinion: Canine Models for Alzheimer’s

By Edward G. Barrett | March 1, 2017

For research on drugs to treat neurodegenerative diseases, dogs offer a better predictor of clinical outcomes. 

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image: Opinion: Reuse and Reduce

Opinion: Reuse and Reduce

By Valerie Speirs | January 16, 2017

Sharing leftover samples from preclinical experiments is one way biomedical researchers can make the most of animal models.

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