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tag cancer gene expression evolution genetics genomics culture
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD
| Feb 9, 2024
| 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD
| Feb 21, 2024
| 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Optimizing Gene Editing with PARP1 CRISPR Plasmids
The Scientist
and Santa Cruz Biotechnology, Inc.
| Jan 24, 2024
| 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee
| Nov 1, 2021
| 8 min read
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
One Protein to Rule Them All
Shelby Bradford, PhD
| Feb 28, 2024
| 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Phenotypic Variation in Cancer Cells Often Not Due to Mutations
Jef Akst
| Oct 26, 2022
| 3 min read
Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests.
MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
Deanna MacNeil, PhD
| Apr 1, 2024
| 3 min read
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
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