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The Scientist

» cancer gene expression

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In the largest study of its kind to date, researchers find more than 850 rare, heritable genetic alterations that can predispose humans to cancer.

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image: Angela Brooks: Splicing Specialist

Angela Brooks: Splicing Specialist

By Diana Kwon | April 1, 2017

At the University of California, Santa Cruz, the researcher combs the cancer genome, looking for weaknesses.

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The tumor biologist’s landmark discovery provided the first clear evidence that genetic mutations could lead to cancer, and gave rise to a crucial cancer drug.

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image: Pulling It All Together

Pulling It All Together

By Kate Yandell | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Another Genetic Cause of Venous Malformations Found

Another Genetic Cause of Venous Malformations Found

By Catherine Offord | March 31, 2016

Mutations in a cancer gene could account for some cases of disfiguring blood vessel abnormalities, scientists show.

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image: Models of Transparency

Models of Transparency

By Joan K. Heath, David Langenau, Kirsten C. Sadler, and Richard White | April 1, 2013

Researchers are taking advantage of small, transparent zebrafish embryos and larvae—and a special strain of see-through adults—to understand the development and spread of cancer.

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image: A Brighter Beacon

A Brighter Beacon

By Edyta Zielinska | April 1, 2012

A novel liquid laser set-up can detect single nucleotide mutations in a cancer gene.

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image: Combing the Cancer Genome

Combing the Cancer Genome

By Carina Storrs | March 1, 2012

A guided tour through the main online resources for analyzing cancer genomics data

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image: Secrets of Breast Cancer Resistance

Secrets of Breast Cancer Resistance

By Tia Ghose | January 4, 2012

A new study shows that breast cancers that become resistant to hormone therapy have different patterns of estrogen receptor binding.

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image: Prime Time for Digital PCR

Prime Time for Digital PCR

By Kelly Rae Chi | December 1, 2011

A rundown of tools on the market and in development

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