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tag age related macular degeneration developmental biology cell molecular biology

Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Jef Akst | Apr 30, 2019 | 2 min read
Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Eye Stem Cell Therapy Moves Ahead
Kate Yandell | Apr 30, 2015 | 4 min read
Researchers inject retinal support cells derived from human embryonic stem cells into the eyes of four men with macular degeneration, bolstering evidence of the experimental treatment’s safety.
How We Age
The Scientist | Mar 1, 2015 | 10+ min read
From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process.
Antibody Alternatives
Paul Ko Ferrigno and Jane McLeod | Feb 1, 2016 | 10+ min read
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Stem Cell Trial Nearly Approved
Jef Akst | Feb 15, 2013 | 1 min read
The first human trial of a treatment using induced pluripotent stem cells has received conditional approval from an institutional review board in Japan.
Forging a Palace for Research on Aging
Eugene Russo | Feb 4, 2001 | 9 min read
Graphic: Cathleen Heard No one can escape one of the few risk factors common to neurodegenerative diseases, heart disease, and many cancers: age. Within the last decade or so, research on aging, once seen as unfeasible and impractical, has become the legitimate purview of many scientists who hope to prolong life, improve quality of later life, and delay humans' decay at the cellular and genetic level. By viewing aging as a fundamental root of other diseases, researchers studying the mechanisms

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