transcription factors, genetics & genomics

The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  

Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.

Scientists identify a transcription factor that plays a key role in increased fruit size.

Selected Images of the Day from the-scientist.com

A single transcription factor regulates a harlequin ladybird’s colors.

A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.

A new algorithm scrutinizes the most hard-to-read segments of the genome.

The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.

Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.

The malnourished microbiome; innate immunity and beige fat; tools for stem cell self-renewal; predicting tomorrow’s PIs; MERS update