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image: Image of the Day: Cooking Up Neurons

Image of the Day: Cooking Up Neurons

By The Scientist Staff | May 11, 2018

Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.

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Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.

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image: Image of the Day: Gene Expression

Image of the Day: Gene Expression

By The Scientist Staff | April 9, 2018

A new algorithm scrutinizes the most hard-to-read segments of the genome.

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Pauses may help cells fine-tune gene expression.

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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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image: Synthetic Sensors

Synthetic Sensors

By Ruth Williams | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Infographic: How to Build a Synthetic Sensor

Infographic: How to Build a Synthetic Sensor

By Ruth Williams | December 1, 2016

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

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image: How These Rodents Got Their Stripes

How These Rodents Got Their Stripes

By Ashley P. Taylor | November 2, 2016

The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38

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