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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Three-Parent IVF Advances

Three-Parent IVF Advances

By | November 30, 2016

Differences in the replicative advantages conferred by some mitochondrial DNA haplotypes have implications for mitochondrial replacement therapy, researchers report. 

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image: Week in Review: October 17–21

Week in Review: October 17–21

By | October 21, 2016

Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds

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image: From Stem Cell to Oocyte In a Dish

From Stem Cell to Oocyte In a Dish

By | October 17, 2016

For the first time, scientists generate functional mouse eggs from stem cells in culture.

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image: A Scrambled Mess

A Scrambled Mess

By | May 1, 2016

Why do so many human eggs have the wrong number of chromosomes?

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image: Next Generation: Sperm-Catching Beads

Next Generation: Sperm-Catching Beads

By | April 27, 2016

Sperm-binding, peptide–coated beads work as an implantable contraception device in mice and as a means of selecting human sperm for assisted reproduction techniques, researchers show. 

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image: Oocytes and Obesity

Oocytes and Obesity

By | February 10, 2015

Eggs from excessively overweight mothers suffer mitochondrial damage that can be averted with pharmacological intervention, a mouse study finds. 

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image: Gravity Determines Cell Size

Gravity Determines Cell Size

By | October 29, 2013

Researchers show that cells may have evolved to be small because of gravitational forces.

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image: Why Women’s Eggs Don’t Last

Why Women’s Eggs Don’t Last

By | February 13, 2013

As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.

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