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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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Scientists are beginning to unravel the ways in which we develop a healthy relationship with the bugs in our bodies.

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image: Contributors

Contributors

By | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.

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image: David Julius Probes the Molecular Mechanics of Pain

David Julius Probes the Molecular Mechanics of Pain

By | January 1, 2018

For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.

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image: Swearing Off Pain

Swearing Off Pain

By | January 1, 2018

Author Emma Byrne runs down the benefits of cursing, among them an enhanced ability to withstand pain.

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image: Ten-Minute Sabbatical

Ten-Minute Sabbatical

By | January 1, 2018

Take a break from the bench to puzzle and peruse.

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image: Why Swearing and Pain Go Hand in Hand

Why Swearing and Pain Go Hand in Hand

By | January 1, 2018

Screaming obscenities when you stub your toe makes perfect biological sense.

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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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image: New Resource Ranks Chemical Probes for Human Proteins

New Resource Ranks Chemical Probes for Human Proteins

By | December 14, 2017

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

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