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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

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Scientists are beginning to unravel the ways in which we develop a healthy relationship with the bugs in our bodies.

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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