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tag lost colony culture immunology evolution cell molecular biology

Lost Colonies
Anna Azvolinsky | Oct 1, 2015 | 10+ min read
Next-generation sequencing has identified scores of new microorganisms, but getting even abundant bacterial species to grow in the lab has proven challenging.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  
New Molecular Tools Enable Researchers To Correlate Viruses, Diseases
Karen Young Kreeger | Feb 4, 1996 | 7 min read
Viruses, Diseases Author: Karen Young Kreeger Sidebar: Professional Resources for Viral Disease Researchers In the mid- to late 1980s, numerous correlations were discovered between viruses and various types of cancers. For example, Epstein-Barr virus was associated with nasopharyngeal carcinoma and B-cell lymphoma, hepatitis B virus with liver cancer, and human papillomavirus with cervical cancer. Now, a decade later, basic and clinical scientists are finding out that viruses may also play a r
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Stem Cell Discoveries Stir Debate
Douglas Steinberg | Nov 12, 2000 | 9 min read
Editor's Note: This is the first of two articles on questions raised by recent stem cell discoveries. The second article, focusing on various organs and the nervous system, will appear in the Nov. 27 issue of The Scientist. Researchers first isolated embryonic stem cells (ESCs) from mouse blastocysts almost 20 years ago, and a paper announcing the discovery of human ESCs emerged in 1998. Adult-derived stem cells (ASCs) have since become the rage in certain quarters of biology, with unexpected--
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

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