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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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Scientists are beginning to unravel the ways in which we develop a healthy relationship with the bugs in our bodies.

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image: Contributors

Contributors

By | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.

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image: David Julius Probes the Molecular Mechanics of Pain

David Julius Probes the Molecular Mechanics of Pain

By | January 1, 2018

For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Painful Realities

Painful Realities

By | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

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image: Prizes and Penalties

Prizes and Penalties

By | January 1, 2018

Life is filled with pleasure and pain. Science and society are struggling mightily with both.

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image: Swearing Off Pain

Swearing Off Pain

By | January 1, 2018

Author Emma Byrne runs down the benefits of cursing, among them an enhanced ability to withstand pain.

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