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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

3 Comments

image: Targeted ER Breakdown

Targeted ER Breakdown

By Ashley P. Taylor | June 17, 2015

Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 

1 Comment

image: How Autophagy Works

How Autophagy Works

By Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | February 1, 2012

There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. 

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image: On the Menu

On the Menu

By Mary Beth Aberlin | February 1, 2012

Digestion on the cellular level: two mysteries examined

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The Enigmatic Membrane

By Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | February 1, 2012

Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.

6 Comments

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