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tag neglected tropical diseases cell molecular biology genetics genomics neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Antibody Alternatives
Paul Ko Ferrigno and Jane McLeod | Feb 1, 2016 | 10+ min read
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.
Molecular Parasitology: A Decade Of Detailed Study Begins To Pay Off
Karen Young Kreeger | Apr 28, 1996 | 9 min read
Begins To Pay Off Parasites evoke a gut reaction, both literally and figuratively. The synonyms for the worms, insects, and protozoans that survive off the life force of other animals are skin-crawling and stomach-churning: bloodsuckers and leeches, to name a few. And it's not by accident that these words evoke such feelings. Once they are firmly ensconced in various viscera, internal parasites produce a range of debilitating and deadly symptoms. Such conditions are more than metaphorical for
Bonn to battle Neurodegeneration
Annette Tuffs | Jan 12, 2009 | 6 min read
Bonn to battle Neurodegeneration A new research center to combat dementia joins a network of neuroscience institutes along the Rhine axis. By Annette Tuffs The view from Venusberg hill, the site of the new German Helmholtz Center for Neurodegenerative Diseases at University Hospital. It is the disease of forgetting—and was for a long time a forgotten disease. Dementia, the seemingly inevitable loss of memory and personality asso

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