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tag alternative splicing ecology genetics genomics microbiology developmental biology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Alternative Splicing Goes Mainstream
Sam Jaffe | Dec 14, 2003 | 10 min read
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly 30,000-gene genome to produce the dizzying variety of proteins that some believe is necessary to produce beings as complex as humans. Alternative splicing--the post-transcriptional editing process that can result in various mRNAs--was previously seen as an interesting but relatively uncommon sidesh
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Bioinformatics, Genomics, and Proteomics
Christopher Smith | Nov 26, 2000 | 10+ min read
Data Mining Software for Genomics, Proteomics and Expression Data (Part 1) Data Mining Software for Genomics, Proteomics and Expression Data (Part 2) High-throughput (HT) sequencing, microarray screening and protein expression profiling technologies drive discovery efforts in today's genomics and proteomics laboratories. These tools allow researchers to generate massive amounts of data, at a rate orders of magnitude greater than scientists ever anticipated. Initiatives to sequence entire genom
Pushing Proteomics
Jim Kling | Apr 14, 2002 | 4 min read
Genomics is slowly but surely moving off center stage, replaced by proteomics. Though proteomics is a young field that hasn't fully found its stride, two new developments provide glimpses of the future. At the end of February, attendees of the Cambridge Healthtech Institute (CHI) Genome Tri-Conference 2002 in Santa Clara, Calif., got their first glimpse of the Protein Atlas of the Human Genome™. Developed by Abingdon, UK-based Confirmant Ltd.—a joint venture of Abingdon, UK-based Ox
Bioengineered Bugs A 'Brisk Trade' In Applied and Basic Entomology
Karen Young Kreeger | Sep 17, 1995 | 7 min read
if (n == null) The Scientist - Beyond the Fruit Fly The Scientist 9[18]:13, Sep. 18, 1995 Research Beyond the Fruit Fly By Karen Young Kreeger Of all the animal species described thus far by scientists, insects account for nearly five-sixths. Nearly 1 million are already identified, with taxonomists estimating another 1 million to go. Despite their ubiquity on Earth, the study of insects has only recently been married to the explosion of molecular biologic
More Researchers Are 'Transitioning' Into Sales Careers
Ricki Lewis | Nov 13, 1994 | 7 min read
Dorothy Rodmann, a career-services consultant at the Washington, D.C.-based American Chemical Society (ACS), is seeing transitioning becoming a necessity for an increasing number of chemists. "In light of what has been happening in the job market -downsizing and strategic changes in direction [among chemical companies]--many chemists are looking at ways to move in different directions, and use their chemical knowledge and skills, of
More Researchers Are 'Transitioning' Into Sales Careers
Ricki Lewis | Nov 13, 1994 | 7 min read
Dorothy Rodmann, a career-services consultant at the Washington, D.C.-based American Chemical Society (ACS), is seeing transitioning becoming a necessity for an increasing number of chemists. "In light of what has been happening in the job market -downsizing and strategic changes in direction [among chemical companies]--many chemists are looking at ways to move in different directions, and use their chemical knowledge and skills, of

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