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Researchers were able to slow tumor growth in a mouse model of human ovarian cancer. 

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By Shawna Williams | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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image: Making Micromotors Biocompatible

Making Micromotors Biocompatible

By Jyoti Madhusoodanan | June 1, 2016

Researchers are developing potent ways to fuel and control the movement of micromotor devices.

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image: RNA Ebola Drug Clears Animal Study

RNA Ebola Drug Clears Animal Study

By Jef Akst | April 24, 2015

The short interfering RNA-based therapy TKM-Ebola protects monkeys from the viral strain still circulating in West Africa.

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image: FDA OKs siRNA Ebola Drug

FDA OKs siRNA Ebola Drug

By Kerry Grens | September 23, 2014

The US Food and Drug Administration gives the green light to deploy an experimental short interfering RNA treatment against Ebola.

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image: Entry Requirements

Entry Requirements

By Nicholette Zeliadt | September 1, 2014

Recent developments in cell transfection and molecular delivery technologies

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image: Marburg Drug Shows Promise

Marburg Drug Shows Promise

By Jyoti Madhusoodanan | August 22, 2014

Monkeys infected with lethal doses of Marburg virus were rescued by an experimental siRNA-based therapeutic, a study shows.

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image: RNAi Remedy Lowers Cholesterol

RNAi Remedy Lowers Cholesterol

By Abby Olena | October 3, 2013

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

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image: Gene Silencing Is Golden

Gene Silencing Is Golden

By Carina Storrs | August 1, 2013

A beginner’s how-to on RNAi screening in mammalian cells

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image: Shushing RNA

Shushing RNA

By Edyta Zielinska | August 1, 2013

The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.

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