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tag defense disease medicine immunology genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn
| Sep 30, 2021
| 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
New Strategies to Discover Human Disease Genes
The Scientist
| Oct 16, 2023
| 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Woman Seemingly Cured of HIV After Umbilical Cord Transplant
Natalia Mesa, PhD
| Feb 16, 2022
| 3 min read
Umbilical cord blood may be a good alternative to bone marrow transplants for treating HIV in patients with HIV and cancer.
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn
| Nov 18, 2021
| 3 min read
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD
| Jan 18, 2024
| 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
A Movable Defense
Eugene V. Koonin and Mart Krupovic
| Jan 1, 2015
| 10 min read
In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.
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