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tag proteome culture developmental biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Pushing Proteomics
Jim Kling | Apr 14, 2002 | 4 min read
Genomics is slowly but surely moving off center stage, replaced by proteomics. Though proteomics is a young field that hasn't fully found its stride, two new developments provide glimpses of the future. At the end of February, attendees of the Cambridge Healthtech Institute (CHI) Genome Tri-Conference 2002 in Santa Clara, Calif., got their first glimpse of the Protein Atlas of the Human Genome™. Developed by Abingdon, UK-based Confirmant Ltd.—a joint venture of Abingdon, UK-based Ox
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Pursuing Proteomes
Deborah Wilkinson | Jun 11, 2000 | 9 min read
Bio-Rad's PROTEAN® IEF System provides 2-D electrophoretic separation as part of the ProteomeWorks System Australian postdoctoral fellow Marc Wilkins coined the term "proteome" in the mid-'90s, referring to the total set of proteins expressed in a given cell at a given time. The term took hold, and a new scientific discipline was born. In proteomic studies, all the proteins from a given cell, organelle, or tissue are analyzed simultaneously with respect to properties such as expression leve
Automation Advances in Proteomics
Aileen Constans | Aug 24, 2003 | 10 min read
Courtesy of the Institute for Systems Biology  MOVING FORWARD: The LCQ Deca XP, an electrospray ionization/ion trap mass spectrometer from Thermo Finnigan The sheer number of new protein-focused mass spectrometry (MS) instruments introduced last year is a testament to the growing importance of the technique in proteomics research. Coupled to this trend is a growing need for automation of upfront sample preparation to feed these analytical machines. From the specialized academic lab to hi
Time-Lapse Proteomics
Chandra Shekhar | Mar 1, 2007 | 4 min read
Isotope labeling and mass spectrometry unite to track proteome dynamics.
On the Fast Track in Functional Proteomics
A. J. S. Rayl | Apr 1, 2001 | 8 min read
Graphic: Leza Berardone Researchers in Canada and Denmark are employing mass spectrometry, three-dimensional tissue biology, and supercomputing to blaze a trail in functional proteomics research. In the process, they're putting their company, MDS Proteomics Inc., on the fast track in the latest race to develop new drug targets and eventually better treatments for all kinds of diseases. By using this combination of technologies, MDS Proteomics is accelerating the process of identifying, analyzin
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Bioinformatics, Genomics, and Proteomics
Christopher Smith | Nov 26, 2000 | 10+ min read
Data Mining Software for Genomics, Proteomics and Expression Data (Part 1) Data Mining Software for Genomics, Proteomics and Expression Data (Part 2) High-throughput (HT) sequencing, microarray screening and protein expression profiling technologies drive discovery efforts in today's genomics and proteomics laboratories. These tools allow researchers to generate massive amounts of data, at a rate orders of magnitude greater than scientists ever anticipated. Initiatives to sequence entire genom

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