Leslie Pray | Jun 24, 2001 | 6 min read
The Bcl-2 protein family members Bax and Bak play an important role in regulating apoptosis.1,2 But following their discovery in the 1990s, they did not take center stage because researchers didn't anticipate their role as "critical effectors of programmed cell death," says Craig Thompson, scientific director of the Abramson Family Cancer Research Institute at the University of Pennsylvania. But the limelight is now upon them as Thompson and his colleagues at the Abramson Institute, in collabora