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tag in vitro fertilization ivf evolution immunology culture

One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Preimplantation Genetic Diagnosis
Philip Hunter | Jun 20, 2004 | 6 min read
FISHING FOR A HEALTHY BABY:Courtesy of the Reproductive Science Center of the San Francisco Bay Area, http://www.rscbayarea.comMulticolor Fluorescence in Situ Hybridization (FISH) can detect chromosomal abnormalities, such as aneuploidy, in cells removed from a developing embryo.Fast improving techniques for detecting genetic and chromosomal abnormalities via preimplantation genetic diagnosis (PGD) may boost the success rate of in vitro fertilization (IVF). Some clinics report a twofold to three
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
NIH loosens stem cell consent rules
Elie Dolgin | Jul 5, 2009 | 3 min read
Final rules for human embryonic stem (ES) cell research, announced this afternoon (July 6) by the National Institutes of Health, require strict documentation detailing voluntary donation of embryos leftover from in-vitro fertilization procedures, but they also contain a mechanism for approving individual cell lines that don't meet the letter of the law but still adhere to the spirit of informed consent. Human embryonic stem cellsImage: Wikimedia/PLoSThe draft guidelines proposed in April expli
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next
Week in Review: January 27–31
Tracy Vence | Jan 31, 2014 | 3 min read
Stimulus-triggered pluripotency; antioxidants speed lung tumor growth; the importance of seminal vesicles; how a plant pathogen jumps hosts
Human Pluripotent Cells Pass Safety Test
Douglas Steinberg | Sep 1, 2002 | 7 min read
Image: ©2001 MacMillan Publishers Ltd.  PLURIPOTENT-CELL PIPELINE: To obtain embryonic germ cells, researchers culture primordial germ cells (PGCs) dissected from the genital ridge. If left in situ, a PGC develops into spermatozoa or ova after its imprints have been erased and reestablished. Embryonic stem cells come from the blastocyst's inner cell mass. (Reprinted with permission, Nature 414:122-8, 2001) Because the science is hard and the politics mean, progress in understanding
More than Sperm Support
Jef Akst | Jan 27, 2014 | 4 min read
Male mice lacking seminal vesicles father fewer offspring, and their sons suffer from abnormal metabolism into adulthood.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

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