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Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  

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image: Researchers Produce Alpaca Antibodies Using Yeast

Researchers Produce Alpaca Antibodies Using Yeast

By Catherine Offord | February 14, 2018

With multiple applications in biomedicine, the antibodies can now be made quickly, cheaply, and without the need for an alpaca or one of its relatives.

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Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By Catherine Offord | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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image: A Triple Threat

A Triple Threat

By Ashley P. Taylor | May 22, 2017

The mosquitoes that carry Zika may be able to transmit two other viruses at the same time.

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The antibodies bind conserved viral parts, allowing them to neutralize all five Ebola types.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By Ruth Williams | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Image of the Day: Feeding Time

Image of the Day: Feeding Time

By The Scientist Staff | January 10, 2017

Scientists are working to improve the abilities of therapeutic antibodies to flag cancer cells (orange) for destruction by macrophages (blue).  

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image: Antibody Shows Promise For Combatting Diverse Strains Of HIV

Antibody Shows Promise For Combatting Diverse Strains Of HIV

By Joshua A. Krisch | November 18, 2016

In preclinical trials, the N6 antibody neutralized 98 percent of 181 HIV strains tested.

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