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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Sensory Biology Around the Animal Kingdom
The Scientist | Sep 1, 2016 | 10+ min read
From detecting gravity and the Earth’s magnetic field to feeling heat and the movement of water around them, animals can do more than just see, smell, touch, taste, and hear.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Beyond Film: Laboratory Imagers
Jorge Cortese | Apr 1, 2002 | 9 min read
Years ago, researchers had only one data-imaging option: autoradiography. These scientists tagged samples—whether nucleic acid, protein, cell, or tissue—with radioactive labels, and captured images on film. Safety concerns, convenience, and sensitivity, spurred the development of alternative techniques, and today, researchers can choose from a range of options, including fluorescence, chemifluorescence, and chemiluminescence, in addition to autoradiography. Fluorescence occurs when
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
How Cells Find Their Way
Laura Defrancesco | Sep 2, 2001 | 5 min read
Organisms need to sense their environment. By sensing, they can develop, heal wounds, protect against invaders, and create blood vessels. Chemotaxis, or directional sensing, allows cells to detect chemicals with exquisite sensitivity. Some chemotactic cells can sense chemical gradients that differ by only a few percent from a cell's front to its back. Although discovery of the molecule types involved in chemotaxis, as with other kinds of cell signaling events, has mounted, the details of how thi
Top 10 Innovations 2012
The Scientist | Dec 1, 2012 | 10+ min read
The Scientist’s 5th installment of its annual competition attracted submissions from across the life science spectrum. Here are the best and brightest products of the year.
Six Scientists Are Added To Ranks Of Prestigious MacArthur Fellows
Karen Young Kreeger | Sep 1, 1996 | 9 min read
SOLVING REAL-WORLD PROBLEMS: MacArthur fellow Vonnie McLoyd's research combines concepts in socioeconomics, psychology, and anthropology. This year's John D. and Catherine T. MacArthur Foundation fellowships will help six scientists advance their cutting-edge, multidisciplinary projects that extend from the ocean depths to distant stars and planets. With grants of about $250,000 or more, the newly named fellows will be able to finance innovative-even maverick-research ideas that might otherwis
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist

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