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tag autism spectrum disorder neuroscience genetics genomics evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Artistic rendition of droplet DNA amplification
Finally, Scientists Sequence Single Cells with Long-Read Technology
Holly Barker, PhD | Mar 8, 2023 | 4 min read
By combining two innovative approaches, researchers can now sequence the full spectrum of mutational differences between individual cells’ genomes.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Colorful DNA strands
Scans of Sundry Variant Types Uncover Autism-Linked Genes
Chloe Williams, Spectrum | Aug 19, 2022 | 5 min read
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Histology showing IL-6 expression
Immune Molecule Alters Cellular Makeup of Human Brain Organoids
Charles Q. Choi, Spectrum | Apr 17, 2023 | 4 min read
The changes may help explain the link between maternal infection and autism, though more research is needed.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Learning Opens the Genome
Ruth Williams | Jan 17, 2018 | 3 min read
Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
The Genes Underlying Autism Are Coming Into Focus
Megan Scudellari | Aug 1, 2016 | 10+ min read
As researchers sequence the DNA of thousands of kids with autism, dozens of genetic subgroups are emerging.

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