The Scientist

» transgenic mice

Most Recent

image: Surrogate Genes Enable Reproduction

Surrogate Genes Enable Reproduction

By Jyoti Madhusoodanan | January 28, 2016

Increasing the expression of two genes from non-Y chromosomes restores spermatogenesis in male mice that lack Y chromosomes.

2 Comments

image: Citation Payola?

Citation Payola?

By Bob Grant | August 18, 2015

A transgenic mouse company is paying researchers who mention its animal models in scientific papers.

1 Comment

image: Passenger Mutations Can Skew Results

Passenger Mutations Can Skew Results

By Kate Yandell | July 7, 2015

Some genetically engineered mice harbor unwanted mutations that hitchhike alongside desired modifications, affecting experimental outcomes.

3 Comments

image: Visualizing X Chromosome Inactivation

Visualizing X Chromosome Inactivation

By Abby Olena | January 21, 2014

Researchers develop mouse lines to help them see whether the maternal or paternal X chromosome is inactivated.

0 Comments

image: Sperm on Lockdown

Sperm on Lockdown

By Abby Olena | December 4, 2013

In a proof-of-principle study, genetic deletion of two genes renders male mice infertile by preventing sperm transport through the vas deferens.

0 Comments

image: More-Primitive Stem Cells Produced

More-Primitive Stem Cells Produced

By Kate Yandell | September 11, 2013

Reprogramming cells within live mice yields a new type of induced pluripotent stem cell.

0 Comments

image: Cranking Out New Models

Cranking Out New Models

By Kate Yandell | May 6, 2013

Scientists make mice strains with multiple mutations in less than a month without using embryonic stem cells.

0 Comments

image: Speaking of Science

Speaking of Science

By The Scientist Staff | May 1, 2013

May 2013's selection of notable quotes

3 Comments

image: Review: <em>Errors of the Human Body</em>

Review: Errors of the Human Body

By Jef Akst | April 11, 2013

This dramatic science fiction film follows a grieving father using his research to understand his infant son’s gruesome death—and explores the culture and ethics of science along the way.

5 Comments

image: Flickering Neurons

Flickering Neurons

By Ruth Williams | February 1, 2013

Fluorescent calcium sensors in transgenic mice give a real-time readout of neuronal activity.

1 Comment

Popular Now

  1. Two University of Rochester Professors Resign in Protest
  2. Dartmouth Professor Investigated for Sexual Misconduct Retires
  3. Theranos Leaders Indicted For Fraud
    The Nutshell Theranos Leaders Indicted For Fraud

    Federal prosecutors filed criminal charges that allege the company’s promise to revolutionize blood testing swindled investors out of hundreds of millions of dollars and put patients in danger.

  4. Koko the Signing Gorilla Dies at 46