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image: CRISPR Trial for Cancer Patients Proposed

CRISPR Trial for Cancer Patients Proposed

By | January 19, 2018

US researchers could become the first outside China to use the gene-editing technique in the clinic. 

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

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The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

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image: Image of the Day: Van Gogh Microscopy

Image of the Day: Van Gogh Microscopy

By | January 10, 2018

Scientists identify the cells that give rise to the soft tissue cancer rhabdomyosarcoma. 

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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The goal is to house patients’ follicles in a specially designed tissue matrix and reinsert them after treatment.

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image: High-Throughput Epigenetics Analyses

High-Throughput Epigenetics Analyses

By | January 1, 2018

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

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image: Contributors

Contributors

By | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.

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image: David Julius Probes the Molecular Mechanics of Pain

David Julius Probes the Molecular Mechanics of Pain

By | January 1, 2018

For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.

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