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Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

transcriptional regulation, cell & molecular biology

Image of the Day: Switch Gears
Sukanya Charuchandra | Sep 10, 2018 | 1 min read
A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.
Paused RNA Polymerase Quashes New Initiation of Transcription
Shawna Williams | Oct 1, 2017 | 2 min read
Pauses may help cells fine-tune gene expression.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Nuclear Pores Come into Sharper Focus
André Hoelz and Daniel H. Lin | Dec 1, 2016 | 10 min read
Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.
Another Role for ApoE?
Ashley P. Taylor | Jan 20, 2016 | 3 min read
Key Alzheimer’s disease–related protein may be a transcriptional regulator.
Fearless about Folding
Anna Azvolinsky | Jan 1, 2016 | 9 min read
Susan Lindquist has never shied away from letting her curiosity guide her research career.
Enhanced Enhancers
Eric Olson | Nov 1, 2014 | 3 min read
The recent discovery of super-enhancers may offer new drug targets for a range of diseases.
Week in Review: March 31–April 4
Tracy Vence | Apr 4, 2014 | 3 min read
Transcriptional landscape of the fetal brain; how a parasitic worm invades plants; difficulties reproducing “breakthrough” heart regeneration method; oxytocin and dishonesty
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