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tag malaria prevention developmental biology genetics genomics microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Molecule of DNA forming inside the test tube equipment.3d rendering,conceptual image.
EvaGreen® Dye: The Swiss Army Knife of qPCR
Biotium | Mar 1, 2024 | 7 min read
A green fluorescent dye with a novel DNA binding mechanism improves signal-to-noise in different DNA amplification assays.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Parasitologist, Reprogrammed: A Profile of David Roos
Anna Azvolinsky | Mar 1, 2018 | 8 min read
After discovering a novel organelle found in protozoan parasites, the University of Pennsylvania’s Roos created a widely used eukaryotic pathogen database.
Researchers Blast Open Pathogen Genome
Barry Palevitz | Aug 18, 2002 | 6 min read
Image: Courtesy of Tim Elkins BRUTE FORCE: Remnant of an appressorium formed on Mylar. The appressorium produced a peg-like extension that penetrated the film, leaving a round hole. (Reprinted with permission, Annual Review of Microbiology, 50:491-512, 1996.) "The Lord shall smite thee with a consumption, and with a fever, and with an inflammation, and with an extreme burning, and with the sword, and with BLASTING, and with mildew; and they shall pursue thee until thou perish." Deuteronom
Scientists Refining Methods For Genetically Altering Insects
Harvey Black | Oct 12, 1997 | 8 min read
FROM LAB TO FIELD: Florida's Marjorie Hoy holds a dish containing several hundred Western predatory mites, which she transformed by injecting a plasmid containing a gene directly into females' ovaries. Creating transgenic insects is seen by some scientists as a new way to manage and possibly eradicate enduring problems such as malaria and agricultural damage from the Mediterranean fruit fly. Researchers appear to be making significant strides in refining the technique. Meanwhile, critics are r
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Collaborative Efforts Under Way To Combat Malaria
Alison Mack | May 11, 1997 | 8 min read
Sidebars Malaria: A Statistical Index Funding Agencies For Malaria Research Researchers in the field lament what they call gross underfunding, but say a joint approach will help ensure that avaliable monies are well spent. After several years of declining interest in malaria research and decreasing support for such studies, the field is gaining much-needed momentum. Spurred in part by an international conference held in Dakar, Senegal, in January, funding agencies and scientists around the gl

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