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tag island dwarfism disease medicine cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa, PhD | Mar 15, 2022 | 7 min read
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Progress In Medicine Unites Recipients Of 1997 Lasker Awards
Stephen Hoffert | Oct 26, 1997 | 8 min read
The Albert and Mary Lasker Foundation honored three medical researchers at an awards luncheon on September 26 in New York. According to a foundation official, the 1997 award winners represent the distinct approaches and scientific perspectives that must combine in the fight against disease. Victor A. McKusick, a professor of genetics at Johns Hopkins University, was given the Special Achievement in Medical Science Award; Mark S. Ptashne, the Ludwig Professor of Molecular Biology at the Mem

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